Many assignments that are business related would not usually place you in a hostile environments except mostly (OIL/GAS) companies

Many assignments that are business related would not usually place you in a hostile environments except mostly (OIL/GAS companies), but I am reminded of the story of Steve Saint and Jim Elliot who were called to the mission field to reach out to an indigenous people in the jungle, where both brutally lost their lives. (See the book End of the Spear) How or would you accept an assignment that might place you in a hostile environment?